The watermelon is the best tasting supplement regardless of what particular supplement your talking about.
To get the most out of it, in my humble opinion, is to put about 5 scoops into 16 ounces of water in the morning on an empty stomach (substituting breakfast altogether). I've been doing this for a few months and I've dropped percentages of fat whilst keeping, or even gaining, more muscle to the effect of being ripped to hell.
Watermelon Xtend is so good, in fact, that I occationally mix it into a preworkout "NO" formula just to make it taste better. I've found that this amplifies the workout, for whatever reason.
The best usage is 1) in the morning (fat metabolism) 2) preworkout (energy substrate and anabolic potentiation) and 3) 20-30 min prior to taking a post-workout shake (dramatically increased protein synthesis).
-TheDiesel |