Diindolylmethane (DIM) is formed by acid catalyzed dimerization of
indole-3-carbinol. DIM is an indole plant nutrient found in cruciferous
vegetables including broccoli, cabbage, brussels sprouts and cauliflower. Unlike
other plant nutrients, such as soy isoflavones, DIM has unique and
distinct hormonal benefits. DIM appears to support the activity of
specific enzymes that improve estrogen metabolism in both men and women.
Scientific research shows that DIM increases the level of “good”
estrogens (2-hydroxyestrogen) while reducing the level of “bad” estrogens
(16-hydroxyestrogen). Underproduction of 2-hydroxyestrogen in women has been
linked to PMS, mid-life obesity, painful menstruation, recurrent breast pain,
cervical dysplasia, fibroid
tumors, as well as rheumatoid arthritis and systemic lupus erythematosus. In
men, obesity and chronic inflammation have been linked to underproduction of
2-hydroxyestrogen. DIM stimulates more efficient estrogen metabolism.
Supplementing the diet with DIM and eating cruciferous vegetables
increase the specific aerobic metabolism for estrogen, multiplying the chance
for estrogen to be broken down into its beneficial, or “good” estrogen
metabolites. By promoting a healthy estrogen metabolism, DIM adjusts the
balance of estradiol to its “good” metabolites. This may also result in a more
desirable action from testosterone. Testosterone supports energy and mood and
helps sustain interest in sex in both men and women. When supplemental DIM
is taken along with a program of regular exercise, it may help estrogen and
testosterone contribute to good physical conditioning. DIM contributes
to a better metabolism in the most natural way possible by working with your own
hormones and adjusting their action to avoid hormonal imbalance. DIM
helps to eliminate active estrogen from the male body by promoting its
conversion into the “good” metabolites. These metabolites then free up
testosterone by bumping it off the testosterone-binding proteins. The end result
is a healthier balance of testosterone to estrogen and more free
(unbound) testosterone circulating in the body. In scientific studies, high
levels of testosterone and low levels of estrogen have been linked to lean body
mass, an efficient fat-burning metabolism, and low abdominal obesity.
DIM Supplement Facts
Serving Size 1 cap
Servings Per Container 60
Amount Per Serving
DIM (diindolylmethane) 100mg