Scivation, the leaders in Science-based innovative supplements and the
company that brought you Xtend™ introduce ANAGEN™--Not only is ANAGEN backed by numerous scientific
studies and formulated by Scivation Director of Research and
Development Chuck “The Ripper” Rudolph and Derek “Beast” Charlebois,
the compounds in ANAGEN have been proven extremely effective in the
real world by Chuck’s elite athletic clients. Furthermore, it is safe
and 100% side effect free. Sound too good to be true? Read on to find
out how ANAGEN may be the key to unlocking your best gains ever….
Anagen
- 20-Hydroxyecdysterone
- Rhodiola Rosea
- Bacopa Monniera
20-Hydroxyecdysterone
Ecdysterone (ECDY) has been around for a while.
ECDY never really became popular in the United States until recently,
but many users were not impressed. The problem there lies in not
getting enough of the active photoecdysteroid 20-Hydroxyecdysterone.
Companies were using either low percent extracts or not dosing their
capsules high enough. Anecdotal feedback from users who have used a
large amount of 20-Hydroxyecdysterone has been impressive, and here is
why.
What is ECDY?
ECDY
is a photoecdysteroid, which is a type of chemical produced by plants
to defend against insects. Insects that ate plants that produced
certain photoecdysteroids would suffer adverse effects and most likely die. This
means that the plants that did produce photoecdysteroids survived; it made them
stronger. Photoecdysteroids are synthesized by plants through the mevalonate
pathway with acetyl-CoA as a precursor. While humans can produce similar
chemicals using this pathway, they cannot produce photoecdysteroids. 20-Hydroxyecdysterone is a specific photoecdysteroid that has been shown to have many beneficial effects.
Dosing ECDY
Based on our experiences with our athletes, we recommend the following
dosing schedule based upon bodyweight to maximize effectiveness:
| Bodyweight in Lbs. |
Bodyweight in Kg |
Caps of Anagen |
| 100 |
45.45 |
2 |
| 120 |
54.55 |
2-3 |
| 140 |
63.64 |
3 |
| 160 |
72.73 |
3-4 |
| 180 |
81.82 |
4 |
| 200 |
90.91 |
4-5 |
| 220 |
100.00 |
5 |
| 240 |
109.09 |
5-6 |
| 260 |
118.18 |
6 |
| 280 |
127.27 |
6 |
| 300 |
136.36 |
6-7 |
Rhodiola Rosea
Rhodiola
Rosea belongs to the plant family Crassulaceae and has been used for
centuries in Russia, Scandinavia, and other eastern countries in
traditional medicine. Rhodiola Rosea is known as an adatogen, a
substance that increases an organism’s resistance to homeostatic
disturbances. Rhodiola Rosea has been shown to:
- Increase physical working capacity (Abidov 2003)
- Improve endurance exercise performance (De Bock 2004)
- Decrease fatigue (Spasov 2000)
Bacopa Monnieri
Bacopa
Monnieri, an adaptogen like Rhodiola, is also a traditional Ayurvedic medicine
used for centuries.
The Ultimate Adaptogen
Based on our
findings, we feel that you need a higher dose to reap the extensive
benefits ecdysterone has to offer. Through research and
experimentation, Scivation developed ANAGEN to help their athletes and
customers achieve the gains they always dreamed of. The addition of
Bacopa Monnieri and Rhodiola Rosea to Ecdysterone adds a synergy that
will help you cope with the stresses of training and diet and achieve
the most significant, healthiest gains of your life.
Supplement Facts
Serving Size: 1 Vegetarian Capsule
Servings Per Container: 90
Amount Per Serving % DV
Cyanotis Vaga (Supplying 60% [100mg]
20-beta-hydroxyecdysterone [HPLC tested]) 167
mg †
Rhodiola Rosea (3% rosavins and 1% salidrosides) 100
mg †
Bacopa Monniera (20:1 Extract) 50
mg †
† Daily Value Not Established.
References:
Abidov M, Crendal F, Grachev S, Seifulla R, Ziegenfuss T. Effect of
extracts from Rhodiola rosea and Rhodiola crenulata (Crassulaceae)
roots on ATP content in mitochondria of skeletal muscles. Bull Exp Biol
Med. 2003 Dec;136(6):585-7.
Chen Q, Xia Y, Qiu Z. Effect of ecdysterone on glucose metabolism in
vitro. Life Sci. 2006 Feb 2;78(10):1108-13. Epub 2005 Oct 24.
De Bock K, Eijnde BO, Ramaekers M, Hespel P. Acute Rhodiola rosea
intake can improve endurance exercise performance. Int J Sport Nutr
Exerc Metab. 2004 Jun;14(3):298-307.
Dinan L. 2001, Phytoecdysteroids: biological aspects. Phytochemistry
57:325-339
Hikino H, Arihara S, Takemoto T. 1969 Ponasteroside A, a glycoside of
insect metamorphosing substance from Pteridium aquilinum var.
latiusculum: structure and absolute configuration. Tetrahedron
25(17):3909-17
Kelly GS. Rhodiola rosea: a possible plant adaptogen. Altern Med Rev.
2001 Jun;6(3):293-302.
Kholodova YD 2001, Phytoecdysteroids: biological effects,application in
agriculture and complementary medicine. Ukr Biokhim Z. 73(3):21-29
Lafont R & L Dinan 2003, Practical uses for ecdysteroids in mammals
including humans: an update. Journal of Insect Science 3:7, Available
online: insectscience.org/3.7
Mirzaev IuR, Syrov VN, Khrushev SA, Iskanderova SD. [Effect of
ecdystene on parameters of the sexual function under experimental and
clinical conditions] Eksp Klin Farmakol. 2000 Jul-Aug;63(4):35-7.
Russian.
Otaka T, Okui S, Uchiyama M 1969, Stimulation of protein synthesis in
mouse liver by ecdysone. Chemical & Pharmaceutical Bulletin (Japan)
17(1):75-81
Rai D, Bhatia G, Palit G, Pal R, Singh S, Singh HK. Adaptogenic effect
of Bacopa monniera (Brahmi). Pharmacol Biochem Behav. 2003
Jul;75(4):823-30.
Russo A, Izzo AA, Borrelli F, Renis M, Vanella A. Free radical
scavenging capacity and protective effect of Bacopa monniera L. on DNA
damage. Phytother Res. 2003 Sep;17(8):870-5.
Russo A, Borrelli F. Bacopa monniera, a reputed nootropic plant: an
overview.
Phytomedicine. 2005 Apr;12(4):305-17. Review.
Saratikov AS, Krasnov EA. Chapter VIII: Clinical studies of Rhodiola.
In: Saratikov AS, Krasnov EA, editors. Rhodiola rosea is a valuable
medicinal plant (Golden Root). Tomsk, Russia: Tomsk State University
Press; 1987. p. 216-27.
Slama K & R Lafont 1995, Insect hormones - ecdysteroids: their
presence and actions in vertebrates. Eur J Entomol 92:355-377
Spasov AA, Wikman GK, Mandrikov VB, Mironova IA, Neumoin VV. A
double-blind, placebo-controlled pilot study of the stimulating and
adaptogenic effect of Rhodiola rosea SHR-5 extract on the fatigue of
students caused by stress during an examination period with a repeated
low-dose regimen. Phytomedicine. 2000 Apr;
Xiao YY, Beilstein MA, Wang MC, Purintrapiban J, Forsberg NE 2003,
Development of a ponasterone A-inducible gene expression system for
application in cultured skeletal muscle cells. The International
Journal of Biochemistry & Cell Biology 35:79-85
